Tuesday, 8 March 2016

biochemistry - What are known examples of drugs that racemize/stereoconvert in vivo, and how are they converted?



It is known that although only the (S)-enantiomer of the infamous sedative thalidomide possesses teratogenic properties, it is not very useful to administer the pure (R)-enantiomer since it is racemized within the body. Are there other known examples of drugs that are stereoconverted in vivo? How does the body perform the conversion?




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readings - Appending 内 to a company name is read ない or うち?

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