For example consider the bromination of phenol we get the tri-substituted product (even though bromine is deactivating so I suppose it should deactivate the ring with each addition) while sulphonation essentially gives the mono-substituted product (even at high temperatures).
Friday, 13 March 2015
organic chemistry - How do we know whether we will get a mono substituted or tri-substituted product during electrophilic aromatic substitution?
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